INHIBITION OF THE PROTEIN ARGININE METHYLTRANSFERASE PRMT5 IN HIGH-RISK MULTIPLE MYELOMA AS A NOVEL TREATMENT APPROACH

Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach

Multiple myeloma (MM) is an incurable clonal plasma cell malignancy.Subsets of patients have high-risk features linked with dismal outcome.Therefore, the need for effective therapeutic options remains high.Here, we used bio-informatic tools to identify novel targets involved in DNA repair and epigenetics and which are associated with high-risk myel

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Exploring the antioxidant potential of nekemias species extracts on edible oils: In vitro assessment and lipid oxidation inhibition

Synthetic antioxidants have long been used to protect edible oils from oxidation.However, concerns about their potential health risks and environmental impact have led to a growing interest in natural antioxidants.In this study, we explore the antioxidant properties of extracts from four Nekemias plant species: Nekemias grossedentata (AGR), Nekemia

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